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相互作用

Amlodipine-olmesartan-hydrochlorothiazide + Cefpirome

重症度: 軽度

Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome: minor interaction.

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概要

Cefpirome is renally cleared and may theoretically compete with hydrochlorothiazide for tubular secretion. Any change in exposure is unlikely to matter clinically.

この相互作用をわかりやすく説明すると

Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Cefpirome belongs to Anti Bacterial.

エビデンスレベル: Low

なぜ起こるのか

Possible competition for renal organic anion tubular secretion.

対処法

No routine action is needed; monitor renal function in patients with renal impairment.

薬剤師に尋ねること

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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よくある質問

Can I take Amlodipine-olmesartan-hydrochlorothiazide with Cefpirome?

MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefpirome is renally cleared and may theoretically compete with hydrochlorothiazide for tubular secretion. Any change in exposure is unlikely to matter clinically.

How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor renal function in patients with renal impairment.

What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.

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MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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