医薬品リファレンス
Cefpirome
Cefpirome is a medicine in the class anti bacterial. It is used for febrile neutropenia.
- 薬効分類: Anti Bacterial
- 効能・効果: febrile neutropenia
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Anti Bacterial
- 一般的な剤形
- 注射剤
- 一般的な規格
- 1 g, 2 g
- 既知の相互作用
- 45 (中等度: 6 · 軽度: 39)
- 商品名
- 2
- 国・市場
- 1
何に使われるか
作用のしくみ
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
成人の通常用量（添付文書の要約）
1-4 g IV every 12 hours.
妊娠と授乳
- 妊娠
- Unknown No human data; animal studies showed no harm. Product labels say safety in pregnancy is not established and it must not be used in pregnancy. Cephalosporins as a class have not shown birth-defect risk; prefer a better-studied cephalosporin.
- 授乳
- Safe Passes into milk; labels advise stopping breastfeeding or the drug. No infant data. e-lactancia: likely compatible, as cephalosporins reach milk in insignificant amounts; prefer a better-studied cephalosporin, especially with a newborn or preterm infant.
報告されている副作用
- Rash
- Positive Coombs test result without hemolysis
- Elevated alanine aminotransferase
- Hypophosphatemia
注意が必要な方
- If CrCl <60 mL/min, adjust dosage to compensate for slower renal elimination rate
- Caution warranted with history of previous immediate hypersensitivity reactions to cefpirome, cephalosporins, penicillins, or other drugs
- Prescribing drug in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to patient
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (45)
- Amikacin + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
- Acetylsalicylic acid + Cefpirome Minor
- Amlodipine-hydrochlorothiazide-valsartan + Cefpirome Minor
- Amlodipine-olmesartan-hydrochlorothiazide + Cefpirome Minor
- Atenolol-chlorthalidone + Cefpirome Minor
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Cefpiromeの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Cefpirome used for?
Cefpirome is a medicine in the class anti bacterial. It is used for Febrile neutropenia, Intra-abdominal infections, Pneumonia, Skin infections, Urinary tract infections.
What side effects have been reported with Cefpirome?
Rash, Positive Coombs test result without hemolysis, Elevated alanine aminotransferase, Hypophosphatemia.
Can Cefpirome be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No human data; animal studies showed no harm. Product labels say safety in pregnancy is not established and it must not be used in pregnancy. Cephalosporins as a class have not shown birth-defect risk; prefer a better-studied cephalosporin. Breastfeeding: Safe. Passes into milk; labels advise stopping breastfeeding or the drug. No infant data. e-lactancia: likely compatible, as cephalosporins reach milk in insignificant amounts; prefer a better-studied cephalosporin, especially with a newborn or preterm infant.
What does Cefpirome interact with?
MediHelp lists 45 known interactions for Cefpirome. Moderate: 6 · Minor: 39. The most serious include Amikacin, Bupropion, Bupropion-naltrexone.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
