相互作用
Cefpirome + Dexamethasone-tobramycin
重症度: 中等度
Cefpirome and Dexamethasone-tobramycin: moderate interaction.
最終更新日
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概要
Cefpirome with an aminoglycoside may add to kidney injury risk, as reported for cephalosporin-aminoglycoside combinations generally, particularly in patients with renal impairment.
この相互作用をわかりやすく説明すると
Cefpirome and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpirome belongs to Anti Bacterial; Dexamethasone-tobramycin belongs to Anti Bacterial.
なぜ起こるのか
Possible additive nephrotoxicity; mechanism not firmly established.
対処法
Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、CefpiromeとDexamethasone-tobramycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dexamethasone-tobramycinのその他の相互作用
Cefpiromeのその他の相互作用
よくある質問
Can I take Cefpirome with Dexamethasone-tobramycin?
MediHelp rates the interaction as moderate. Cefpirome and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefpirome with an aminoglycoside may add to kidney injury risk, as reported for cephalosporin-aminoglycoside combinations generally, particularly in patients with renal impairment.
How serious is the interaction between Cefpirome and Dexamethasone-tobramycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
