相互作用
Cefpirome + Gentamicin
重症度: 中等度
Cefpirome and Gentamicin: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Cephalosporins have been reported to add to aminoglycoside nephrotoxicity, though the effect is generally modest with newer agents. Concurrent use may modestly raise the risk of renal impairment, particularly in patients with existing kidney disease or dehydration.
この相互作用をわかりやすく説明すると
Cefpirome and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpirome belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.
なぜ起こるのか
Possible additive renal tubular injury; the mechanism is not firmly established.
対処法
Monitor serum creatinine during combined therapy and adjust doses to renal function. Check gentamicin levels in patients at risk.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefpiromeとGentamicinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Gentamicinのその他の相互作用
Cefpiromeのその他の相互作用
よくある質問
Can I take Cefpirome with Gentamicin?
MediHelp rates the interaction as moderate. Cefpirome and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cephalosporins have been reported to add to aminoglycoside nephrotoxicity, though the effect is generally modest with newer agents. Concurrent use may modestly raise the risk of renal impairment, particularly in patients with existing kidney disease or dehydration.
How serious is the interaction between Cefpirome and Gentamicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine during combined therapy and adjust doses to renal function. Check gentamicin levels in patients at risk.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
