Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Cefpirome
Severity: Minor
Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefpirome is renally cleared and may theoretically compete with hydrochlorothiazide for tubular secretion. Any change in exposure is unlikely to matter clinically.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Cefpirome belongs to Anti Bacterial.
Why it happens
Possible competition for renal organic anion tubular secretion.
What to do
No routine action is needed; monitor renal function in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Other interactions of Cefpirome
- Amikacin + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Cefpirome?
MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefpirome is renally cleared and may theoretically compete with hydrochlorothiazide for tubular secretion. Any change in exposure is unlikely to matter clinically.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor renal function in patients with renal impairment.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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