相互作用
Amoxapine + Dicyclomine
重症度: 中等度
Amoxapine and Dicyclomine: moderate interaction.
最終更新日
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概要
Amoxapine has anticholinergic properties, which add to those of dicyclomine. The combination may cause marked dry mouth, constipation, urinary retention, blurred vision, confusion and tachycardia, particularly in older people.
この相互作用をわかりやすく説明すると
Amoxapine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive muscarinic receptor blockade.
対処法
Monitor for anticholinergic toxicity and consider a lower dicyclomine dose or a less anticholinergic alternative. Take extra care in older patients and those with glaucoma or urinary obstruction.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmoxapineとDicyclomineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dicyclomineのその他の相互作用
よくある質問
Can I take Amoxapine with Dicyclomine?
MediHelp rates the interaction as moderate. Amoxapine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amoxapine has anticholinergic properties, which add to those of dicyclomine. The combination may cause marked dry mouth, constipation, urinary retention, blurred vision, confusion and tachycardia, particularly in older people.
How serious is the interaction between Amoxapine and Dicyclomine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity and consider a lower dicyclomine dose or a less anticholinergic alternative. Take extra care in older patients and those with glaucoma or urinary obstruction.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
