相互作用
Atracurium + Oxytetracycline
重症度: 中等度
Atracurium and Oxytetracycline: moderate interaction.
最終更新日
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概要
Tetracyclines have weak neuromuscular blocking effects, and potentiation of nondepolarising blockers is described mainly in case reports. Clinical significance with oxytetracycline is likely small but could prolong recovery.
この相互作用をわかりやすく説明すると
Atracurium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atracurium belongs to Musculoskeletal; Oxytetracycline belongs to Anti Bacterial.
なぜ起こるのか
Possible calcium chelation and weak presynaptic neuromuscular blockade adding to nondepolarising blockade.
対処法
Monitor neuromuscular function with train-of-four during surgery or ICU use. Adjust atracurium dosing to response.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AtracuriumとOxytetracyclineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Atracuriumのその他の相互作用
Oxytetracyclineのその他の相互作用
よくある質問
Can I take Atracurium with Oxytetracycline?
MediHelp rates the interaction as moderate. Atracurium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetracyclines have weak neuromuscular blocking effects, and potentiation of nondepolarising blockers is described mainly in case reports. Clinical significance with oxytetracycline is likely small but could prolong recovery.
How serious is the interaction between Atracurium and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with train-of-four during surgery or ICU use. Adjust atracurium dosing to response.
What other medicines interact with Atracurium?
MediHelp also lists interactions of Atracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Atracurium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
