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相互作用

Calcium carbonate + Oxytetracycline

重症度: 中等度

Calcium carbonate and Oxytetracycline: moderate interaction.

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概要

Calcium carbonate decreases oxytetracycline absorption and may cause inadequate antibiotic exposure and treatment failure.

この相互作用をわかりやすく説明すると

Calcium carbonate and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Calcium carbonate belongs to Gastrointestinal Tract; Oxytetracycline belongs to Anti Bacterial.

エビデンスレベル: High

なぜ起こるのか

Calcium ions chelate oxytetracycline in the gut, forming insoluble, poorly absorbed complexes.

対処法

Give oxytetracycline at least 2 hours before or 4 hours after calcium carbonate.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Calcium carbonate with Oxytetracycline?

MediHelp rates the interaction as moderate. Calcium carbonate and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium carbonate decreases oxytetracycline absorption and may cause inadequate antibiotic exposure and treatment failure.

How serious is the interaction between Calcium carbonate and Oxytetracycline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oxytetracycline at least 2 hours before or 4 hours after calcium carbonate.

What other medicines interact with Calcium carbonate?

MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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