相互作用
Azithromycin + Dronedarone
重症度: 併用禁忌
Azithromycin and Dronedarone: contraindicated interaction.
最終更新日
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概要
Dronedarone is contraindicated with drugs that lengthen the QT interval, including macrolides such as azithromycin. Together they raise the risk of torsades de pointes and sudden cardiac death.
この相互作用をわかりやすく説明すると
Azithromycin and Dronedarone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Azithromycin belongs to Anti Bacterial; Dronedarone belongs to Cardiovascular.
なぜ起こるのか
Additive QTc prolongation
対処法
Do not co-administer; use a non-macrolide antibiotic without QT effect.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AzithromycinとDronedaroneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Azithromycinのその他の相互作用
Dronedaroneのその他の相互作用
よくある質問
Can I take Azithromycin with Dronedarone?
MediHelp rates the interaction as contraindicated. Azithromycin and Dronedarone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dronedarone is contraindicated with drugs that lengthen the QT interval, including macrolides such as azithromycin. Together they raise the risk of torsades de pointes and sudden cardiac death.
How serious is the interaction between Azithromycin and Dronedarone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; use a non-macrolide antibiotic without QT effect.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Pimozide. The full list is on the Azithromycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
