相互作用
Betamethasone + Moxifloxacin
重症度: 重大
Betamethasone and Moxifloxacin: major interaction.
最終更新日
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概要
Concurrent corticosteroids and fluoroquinolones increase the risk of tendinitis and tendon rupture, notably of the Achilles tendon. Risk is higher in older patients, transplant recipients and those on prolonged or high-dose steroids.
この相互作用をわかりやすく説明すると
Betamethasone and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Betamethasone belongs to Endocrine; Moxifloxacin belongs to Anti Bacterial.
なぜ起こるのか
Both drugs damage tendon tissue and impair collagen turnover, producing additive tendon toxicity.
対処法
Avoid the combination where possible, especially in patients over 60. Instruct patients to stop moxifloxacin and rest at the first sign of tendon pain or swelling.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BetamethasoneとMoxifloxacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Moxifloxacinのその他の相互作用
Betamethasoneのその他の相互作用
よくある質問
Can I take Betamethasone with Moxifloxacin?
MediHelp rates the interaction as major. Betamethasone and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Concurrent corticosteroids and fluoroquinolones increase the risk of tendinitis and tendon rupture, notably of the Achilles tendon. Risk is higher in older patients, transplant recipients and those on prolonged or high-dose steroids.
How serious is the interaction between Betamethasone and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, especially in patients over 60. Instruct patients to stop moxifloxacin and rest at the first sign of tendon pain or swelling.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
