相互作用
Betamethasone + Levofloxacin
重症度: 重大
Betamethasone and Levofloxacin: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Using a fluoroquinolone together with a systemic corticosteroid increases the risk of tendinitis and tendon rupture, particularly of the Achilles tendon. The risk is higher in older adults and transplant patients.
この相互作用をわかりやすく説明すると
Betamethasone and Levofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Betamethasone belongs to Endocrine; Levofloxacin belongs to Anti Bacterial.
なぜ起こるのか
Both drugs have adverse effects on tendon tissue and collagen integrity, and the effects appear to be additive.
対処法
Avoid the combination where possible, especially in patients over 60. Stop levofloxacin and rest the limb if tendon pain or swelling develops.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BetamethasoneとLevofloxacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Levofloxacinのその他の相互作用
Betamethasoneのその他の相互作用
よくある質問
Can I take Betamethasone with Levofloxacin?
MediHelp rates the interaction as major. Betamethasone and Levofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Using a fluoroquinolone together with a systemic corticosteroid increases the risk of tendinitis and tendon rupture, particularly of the Achilles tendon. The risk is higher in older adults and transplant patients.
How serious is the interaction between Betamethasone and Levofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, especially in patients over 60. Stop levofloxacin and rest the limb if tendon pain or swelling develops.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Ibutilide, Thioridazine. The full list is on the Levofloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
