相互作用
Atazanavir + Calcium carbonate
重症度: 中等度
Atazanavir and Calcium carbonate: moderate interaction.
最終更新日
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概要
Atazanavir needs an acidic environment to dissolve, and calcium carbonate raises gastric pH. Reduced atazanavir exposure can lead to virologic failure and resistance.
この相互作用をわかりやすく説明すると
Atazanavir and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atazanavir belongs to Anti Virals; Calcium carbonate belongs to Gastrointestinal Tract.
なぜ起こるのか
Elevated gastric pH decreases the solubility and absorption of atazanavir.
対処法
Give atazanavir at least 2 hours before or 1 hour after the antacid.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、AtazanavirとCalcium carbonateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Calcium carbonateのその他の相互作用
Atazanavirのその他の相互作用
よくある質問
Can I take Atazanavir with Calcium carbonate?
MediHelp rates the interaction as moderate. Atazanavir and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atazanavir needs an acidic environment to dissolve, and calcium carbonate raises gastric pH. Reduced atazanavir exposure can lead to virologic failure and resistance.
How serious is the interaction between Atazanavir and Calcium carbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give atazanavir at least 2 hours before or 1 hour after the antacid.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
