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相互作用

Cefaclor + Warfarin

重症度: 中等度

Cefaclor and Warfarin: moderate interaction.

最終更新日

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概要

Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.

この相互作用をわかりやすく説明すると

Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefaclor belongs to Anti Bacterial; Warfarin belongs to Cardiovascular.

エビデンスレベル: Low

なぜ起こるのか

Not firmly established; possibly reduced gut-derived vitamin K or other effects on warfarin response.

対処法

Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、CefaclorとWarfarinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Cefaclor with Warfarin?

MediHelp rates the interaction as moderate. Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.

How serious is the interaction between Cefaclor and Warfarin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.

What other medicines interact with Cefaclor?

MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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