相互作用
Cholecalciferol + Orlistat
重症度: 中等度
Cholecalciferol and Orlistat: moderate interaction.
最終更新日
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概要
Orlistat blocks dietary fat digestion and thereby reduces absorption of fat-soluble vitamins, including vitamin D. Long-term use can lower vitamin D levels.
この相互作用をわかりやすく説明すると
Cholecalciferol and Orlistat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholecalciferol belongs to Musculoskeletal; Orlistat belongs to Miscellaneous.
なぜ起こるのか
Inhibition of gastrointestinal lipases reduces fat absorption and micellar solubilization of fat-soluble vitamins.
対処法
Take vitamin D at least 2 hours before or after orlistat, for example at bedtime. Monitor 25-hydroxyvitamin D levels and adjust the dose as needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CholecalciferolとOrlistatの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cholecalciferolのその他の相互作用
Orlistatのその他の相互作用
よくある質問
Can I take Cholecalciferol with Orlistat?
MediHelp rates the interaction as moderate. Cholecalciferol and Orlistat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Orlistat blocks dietary fat digestion and thereby reduces absorption of fat-soluble vitamins, including vitamin D. Long-term use can lower vitamin D levels.
How serious is the interaction between Cholecalciferol and Orlistat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take vitamin D at least 2 hours before or after orlistat, for example at bedtime. Monitor 25-hydroxyvitamin D levels and adjust the dose as needed.
What other medicines interact with Cholecalciferol?
MediHelp also lists interactions of Cholecalciferol with, for example, Digoxin, Aluminum hydroxide, Calcium acetate. The full list is on the Cholecalciferol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
