相互作用
Cyclizine + Glycopyrrolate
重症度: 中等度
Cyclizine and Glycopyrrolate: moderate interaction.
最終更新日
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概要
Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.
この相互作用をわかりやすく説明すると
Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cyclizine belongs to Respiratory; Glycopyrrolate belongs to Respiratory.
なぜ起こるのか
Additive muscarinic receptor antagonism.
対処法
Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CyclizineとGlycopyrrolateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cyclizineのその他の相互作用
Glycopyrrolateのその他の相互作用
よくある質問
Can I take Cyclizine with Glycopyrrolate?
MediHelp rates the interaction as moderate. Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.
How serious is the interaction between Cyclizine and Glycopyrrolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Henbane, Sodium oxybate. The full list is on the Cyclizine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
