相互作用
Bethanechol + Glycopyrrolate
重症度: 中等度
Bethanechol and Glycopyrrolate: moderate interaction.
最終更新日
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概要
Glycopyrrolate is a muscarinic antagonist and opposes the effects of bethanechol on the bladder and gut. The result is reduced efficacy of one or both drugs.
この相互作用をわかりやすく説明すると
Bethanechol and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bethanechol belongs to Gastrointestinal Tract; Glycopyrrolate belongs to Respiratory.
なぜ起こるのか
Competitive muscarinic receptor antagonism opposes bethanechol agonism.
対処法
Avoid concurrent use when bethanechol is intended to stimulate motility or bladder emptying. If necessary, monitor clinical response and adjust doses.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、BethanecholとGlycopyrrolateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bethanecholのその他の相互作用
Glycopyrrolateのその他の相互作用
よくある質問
Can I take Bethanechol with Glycopyrrolate?
MediHelp rates the interaction as moderate. Bethanechol and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glycopyrrolate is a muscarinic antagonist and opposes the effects of bethanechol on the bladder and gut. The result is reduced efficacy of one or both drugs.
How serious is the interaction between Bethanechol and Glycopyrrolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use when bethanechol is intended to stimulate motility or bladder emptying. If necessary, monitor clinical response and adjust doses.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
