相互作用
Deflazacort + Lubiprostone
重症度: 軽度
Deflazacort and Lubiprostone: minor interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Lubiprostone can cause diarrhea and corticosteroids promote renal potassium loss, so potassium depletion may be additive. Clinically significant hypokalemia is more likely with prolonged use or other potassium-lowering drugs.
この相互作用をわかりやすく説明すると
Deflazacort and Lubiprostone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deflazacort belongs to Miscellaneous; Lubiprostone belongs to Gastrointestinal Tract.
なぜ起こるのか
Additive potassium loss via renal excretion (corticosteroid) and gastrointestinal fluid loss (lubiprostone-induced diarrhea).
対処法
Monitor serum potassium if diarrhea develops or therapy is prolonged, and replace as needed.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DeflazacortとLubiprostoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Deflazacortのその他の相互作用
- Adenovirus types 4 and 7 live + Deflazacort 併用禁忌
- Bcg vaccine live + Deflazacort 併用禁忌
- Deflazacort + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Deflazacort + Measles mumps and rubella vaccine 併用禁忌
- Deflazacort + Measles mumps and rubella vaccine live 併用禁忌
- Deflazacort + Measles mumps rubella and varicella vaccine live 併用禁忌
Lubiprostoneのその他の相互作用
よくある質問
Can I take Deflazacort with Lubiprostone?
MediHelp rates the interaction as minor. Deflazacort and Lubiprostone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lubiprostone can cause diarrhea and corticosteroids promote renal potassium loss, so potassium depletion may be additive. Clinically significant hypokalemia is more likely with prolonged use or other potassium-lowering drugs.
How serious is the interaction between Deflazacort and Lubiprostone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if diarrhea develops or therapy is prolonged, and replace as needed.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。