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相互作用

Deflazacort + Lubiprostone

重症度: 軽度

Deflazacort and Lubiprostone: minor interaction.

最終更新日

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概要

Lubiprostone can cause diarrhea and corticosteroids promote renal potassium loss, so potassium depletion may be additive. Clinically significant hypokalemia is more likely with prolonged use or other potassium-lowering drugs.

この相互作用をわかりやすく説明すると

Deflazacort and Lubiprostone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Deflazacort belongs to Miscellaneous; Lubiprostone belongs to Gastrointestinal Tract.

エビデンスレベル: Low

なぜ起こるのか

Additive potassium loss via renal excretion (corticosteroid) and gastrointestinal fluid loss (lubiprostone-induced diarrhea).

対処法

Monitor serum potassium if diarrhea develops or therapy is prolonged, and replace as needed.

薬剤師に尋ねること

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+会員向け

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アカウントを作成してPro+トライアルを始めると、DeflazacortとLubiprostoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Deflazacort with Lubiprostone?

MediHelp rates the interaction as minor. Deflazacort and Lubiprostone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lubiprostone can cause diarrhea and corticosteroids promote renal potassium loss, so potassium depletion may be additive. Clinically significant hypokalemia is more likely with prolonged use or other potassium-lowering drugs.

How serious is the interaction between Deflazacort and Lubiprostone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if diarrhea develops or therapy is prolonged, and replace as needed.

What other medicines interact with Deflazacort?

MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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