相互作用
Dobutamine + Ergotamine
重症度: 重大
Dobutamine and Ergotamine: major interaction.
最終更新日
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概要
Ergotamine causes potent peripheral and coronary vasoconstriction, and dobutamine stimulates adrenergic receptors, adding vasoconstrictor and pressor effects. The combination can produce severe hypertension and peripheral or cardiac ischaemia.
この相互作用をわかりやすく説明すると
Dobutamine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dobutamine belongs to Cardiovascular; Ergotamine belongs to Central Nervous System.
なぜ起こるのか
Additive vasoconstriction (pharmacodynamic)
対処法
Avoid the combination; if a vasoactive agent is needed in a patient exposed to ergotamine, use the lowest dose and monitor perfusion and blood pressure.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DobutamineとErgotamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dobutamineのその他の相互作用
Ergotamineのその他の相互作用
よくある質問
Can I take Dobutamine with Ergotamine?
MediHelp rates the interaction as major. Dobutamine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ergotamine causes potent peripheral and coronary vasoconstriction, and dobutamine stimulates adrenergic receptors, adding vasoconstrictor and pressor effects. The combination can produce severe hypertension and peripheral or cardiac ischaemia.
How serious is the interaction between Dobutamine and Ergotamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; if a vasoactive agent is needed in a patient exposed to ergotamine, use the lowest dose and monitor perfusion and blood pressure.
What other medicines interact with Dobutamine?
MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
