相互作用
Eltrombopag + Magnesium sulphate
重症度: 中等度
Eltrombopag and Magnesium sulphate: moderate interaction.
最終更新日
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概要
Eltrombopag chelates polyvalent cations in the gut, and oral magnesium sulphate binds it, reducing eltrombopag absorption considerably. Platelet response can fall.
この相互作用をわかりやすく説明すると
Eltrombopag and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eltrombopag belongs to Miscellaneous; Magnesium sulphate belongs to Cardiovascular.
なぜ起こるのか
Chelation of eltrombopag by magnesium in the gastrointestinal tract
対処法
Take eltrombopag at least 2 hours before or 4 hours after magnesium products, and monitor platelet counts.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、EltrombopagとMagnesium sulphateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Magnesium sulphateのその他の相互作用
Eltrombopagのその他の相互作用
よくある質問
Can I take Eltrombopag with Magnesium sulphate?
MediHelp rates the interaction as moderate. Eltrombopag and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eltrombopag chelates polyvalent cations in the gut, and oral magnesium sulphate binds it, reducing eltrombopag absorption considerably. Platelet response can fall.
How serious is the interaction between Eltrombopag and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take eltrombopag at least 2 hours before or 4 hours after magnesium products, and monitor platelet counts.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
