相互作用
Levetiracetam + Pyrilamine
重症度: 中等度
Levetiracetam and Pyrilamine: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Pyrilamine is a first-generation antihistamine that commonly causes drowsiness. With levetiracetam, sedation and impaired alertness may be greater.
この相互作用をわかりやすく説明すると
Levetiracetam and Pyrilamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levetiracetam belongs to Central Nervous System; Pyrilamine belongs to Respiratory.
なぜ起こるのか
Additive central nervous system depression (pharmacodynamic).
対処法
Advise patients to avoid driving or hazardous tasks if drowsy, and consider a non-sedating antihistamine as an alternative.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、LevetiracetamとPyrilamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Levetiracetamのその他の相互作用
Pyrilamineのその他の相互作用
よくある質問
Can I take Levetiracetam with Pyrilamine?
MediHelp rates the interaction as moderate. Levetiracetam and Pyrilamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pyrilamine is a first-generation antihistamine that commonly causes drowsiness. With levetiracetam, sedation and impaired alertness may be greater.
How serious is the interaction between Levetiracetam and Pyrilamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid driving or hazardous tasks if drowsy, and consider a non-sedating antihistamine as an alternative.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。