相互作用
Amisulpride + Pyrilamine
重症度: 軽度
Amisulpride and Pyrilamine: minor interaction.
最終更新日
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概要
Pyrilamine is a first-generation sedating antihistamine. With amisulpride, drowsiness and impaired alertness may be additive, and anticholinergic effects may also accumulate in susceptible patients.
この相互作用をわかりやすく説明すると
Amisulpride and Pyrilamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amisulpride belongs to Central Nervous System; Pyrilamine belongs to Respiratory.
なぜ起こるのか
Additive CNS depression via histamine H1 antagonism and amisulpride's sedative effects.
対処法
Advise patients about drowsiness and to avoid driving if affected. Consider a non-sedating antihistamine if needed.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmisulprideとPyrilamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amisulprideのその他の相互作用
Pyrilamineのその他の相互作用
よくある質問
Can I take Amisulpride with Pyrilamine?
MediHelp rates the interaction as minor. Amisulpride and Pyrilamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pyrilamine is a first-generation sedating antihistamine. With amisulpride, drowsiness and impaired alertness may be additive, and anticholinergic effects may also accumulate in susceptible patients.
How serious is the interaction between Amisulpride and Pyrilamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about drowsiness and to avoid driving if affected. Consider a non-sedating antihistamine if needed.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
