相互作用
Nelarabine + Trastuzumab
重症度: 中等度
Nelarabine and Trastuzumab: moderate interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Nelarabine causes myelosuppression and neurotoxicity. With trastuzumab, neutropenia and infection risk may be increased.
この相互作用をわかりやすく説明すると
Nelarabine and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nelarabine belongs to Oncology; Trastuzumab belongs to Oncology.
なぜ起こるのか
Additive myelosuppression from the cytotoxic agent with trastuzumab.
対処法
Monitor complete blood counts regularly and for signs of infection. Delay or adjust nelarabine dosing for significant cytopenias.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、NelarabineとTrastuzumabの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Trastuzumabのその他の相互作用
Nelarabineのその他の相互作用
よくある質問
Can I take Nelarabine with Trastuzumab?
MediHelp rates the interaction as moderate. Nelarabine and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nelarabine causes myelosuppression and neurotoxicity. With trastuzumab, neutropenia and infection risk may be increased.
How serious is the interaction between Nelarabine and Trastuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts regularly and for signs of infection. Delay or adjust nelarabine dosing for significant cytopenias.
What other medicines interact with Trastuzumab?
MediHelp also lists interactions of Trastuzumab with, for example, Daunorubicin, Doxorubicin liposomal, Doxorubicin. The full list is on the Trastuzumab page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
