相互作用
Fingolimod + Nelarabine
重症度: 中等度
Fingolimod and Nelarabine: moderate interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Nelarabine is a cytotoxic purine analogue causing myelosuppression and neurotoxicity. With fingolimod's lymphocyte-lowering effect, the risk of infection may increase.
この相互作用をわかりやすく説明すると
Fingolimod and Nelarabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Nelarabine belongs to Oncology.
なぜ起こるのか
Additive pharmacodynamic immunosuppression from cytotoxic myelosuppression and lymphocyte sequestration.
対処法
Monitor blood counts and infection signs. Consider interrupting fingolimod during chemotherapy.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、FingolimodとNelarabineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Fingolimodのその他の相互作用
Nelarabineのその他の相互作用
よくある質問
Can I take Fingolimod with Nelarabine?
MediHelp rates the interaction as moderate. Fingolimod and Nelarabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nelarabine is a cytotoxic purine analogue causing myelosuppression and neurotoxicity. With fingolimod's lymphocyte-lowering effect, the risk of infection may increase.
How serious is the interaction between Fingolimod and Nelarabine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and infection signs. Consider interrupting fingolimod during chemotherapy.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Pimozide. The full list is on the Fingolimod page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
