相互作用
Nevirapine + Valoctocogene roxaparvovec
重症度: 重大
Nevirapine and Valoctocogene roxaparvovec: major interaction.
最終更新日
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概要
Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.
この相互作用をわかりやすく説明すると
Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Nevirapine belongs to Anti Virals; Valoctocogene roxaparvovec belongs to Miscellaneous.
なぜ起こるのか
Additive hepatotoxicity; nevirapine can cause hepatocellular injury independent of the gene therapy.
対処法
Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、NevirapineとValoctocogene roxaparvovecの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Nevirapineのその他の相互作用
Valoctocogene roxaparvovecのその他の相互作用
よくある質問
Can I take Nevirapine with Valoctocogene roxaparvovec?
MediHelp rates the interaction as major. Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.
How serious is the interaction between Nevirapine and Valoctocogene roxaparvovec?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
