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Interações medicamentosas

Amlodipine-olmesartan-hydrochlorothiazide + Cefpirome

Gravidade: Leve

Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome: minor interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Cefpirome is renally cleared and may theoretically compete with hydrochlorothiazide for tubular secretion. Any change in exposure is unlikely to matter clinically.

O que esta interação significa em palavras simples

Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Cefpirome belongs to Anti Bacterial.

Nível de evidência: Low

Por que acontece

Possible competition for renal organic anion tubular secretion.

O que fazer

No routine action is needed; monitor renal function in patients with renal impairment.

O que perguntar ao farmacêutico

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

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Perguntas frequentes

Can I take Amlodipine-olmesartan-hydrochlorothiazide with Cefpirome?

MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefpirome is renally cleared and may theoretically compete with hydrochlorothiazide for tubular secretion. Any change in exposure is unlikely to matter clinically.

How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Cefpirome?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor renal function in patients with renal impairment.

What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.

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