Interações medicamentosas
Cefpirome + Streptomycin
Gravidade: Moderada
Cefpirome and Streptomycin: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Cephalosporins given with aminoglycosides have been associated with increased kidney injury in some reports, though the effect is inconsistent and is modest for newer agents. Combination is common in practice.
O que esta interação significa em palavras simples
Cefpirome and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpirome belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.
Por que acontece
Possible additive nephrotoxicity; mechanism is not well established.
O que fazer
Monitor serum creatinine and urine output during combined therapy and adjust the streptomycin dose according to renal function.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Streptomycin
Outras interações de Cefpirome
- Amikacin + Cefpirome Moderada
- Bupropion-naltrexone + Cefpirome Moderada
- Bupropion + Cefpirome Moderada
- Cefpirome + Dexamethasone-tobramycin Moderada
- Cefpirome + Gentamicin Moderada
- Acetylsalicylic acid + Cefpirome Leve
Perguntas frequentes
Can I take Cefpirome with Streptomycin?
MediHelp rates the interaction as moderate. Cefpirome and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cephalosporins given with aminoglycosides have been associated with increased kidney injury in some reports, though the effect is inconsistent and is modest for newer agents. Combination is common in practice.
How serious is the interaction between Cefpirome and Streptomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output during combined therapy and adjust the streptomycin dose according to renal function.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.
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