Interações medicamentosas
Azelastine + Dexchlorpheniramine
Gravidade: Moderada
Azelastine and Dexchlorpheniramine: moderate interaction.
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Resumo
Both are H1 antihistamines, and dexchlorpheniramine is sedating and anticholinergic. Combined use duplicates therapy and increases drowsiness and anticholinergic effects.
O que esta interação significa em palavras simples
Azelastine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azelastine belongs to Respiratory; Dexchlorpheniramine belongs to Respiratory.
Por que acontece
Duplicate H1 antagonism producing additive sedation and anticholinergic effects.
O que fazer
Avoid concurrent use and choose one antihistamine. If unavoidable, monitor for sedation and anticholinergic effects.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Azelastine
Outras interações de Dexchlorpheniramine
- Alprazolam + Dexchlorpheniramine Moderada
- Amisulpride + Dexchlorpheniramine Moderada
- Amitriptyline + Dexchlorpheniramine Moderada
- Amobarbital + Dexchlorpheniramine Moderada
- Asenapine + Dexchlorpheniramine Moderada
- Azelastine-fluticasone + Dexchlorpheniramine Moderada
Perguntas frequentes
Can I take Azelastine with Dexchlorpheniramine?
MediHelp rates the interaction as moderate. Azelastine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are H1 antihistamines, and dexchlorpheniramine is sedating and anticholinergic. Combined use duplicates therapy and increases drowsiness and anticholinergic effects.
How serious is the interaction between Azelastine and Dexchlorpheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose one antihistamine. If unavoidable, monitor for sedation and anticholinergic effects.
What other medicines interact with Azelastine?
MediHelp also lists interactions of Azelastine with, for example, Calcium / magnesium / potassium / sodium oxybates, Methadone, Sodium oxybate. The full list is on the Azelastine page.
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