Interações medicamentosas
Influenza virus vaccine quadrivalent intranasal + Upadacitinib
Gravidade: Contraindicada
Influenza virus vaccine quadrivalent intranasal and Upadacitinib: contraindicated interaction.
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Resumo
The intranasal influenza vaccine is live attenuated, and upadacitinib-related immunosuppression may permit vaccine virus replication and illness. The vaccine response may also be reduced.
O que esta interação significa em palavras simples
Influenza virus vaccine quadrivalent intranasal and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Immunosuppression impairs control of live attenuated virus.
O que fazer
Use an inactivated injectable influenza vaccine instead during upadacitinib therapy.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Upadacitinib
- Abrocitinib + Upadacitinib Contraindicada
- Adenovirus types 4 and 7 live + Upadacitinib Contraindicada
- Baricitinib + Upadacitinib Contraindicada
- Bcg vaccine live + Upadacitinib Contraindicada
- Cyclosporine + Upadacitinib Contraindicada
- Dengue vaccine + Upadacitinib Contraindicada
Perguntas frequentes
Can I take Influenza virus vaccine quadrivalent intranasal with Upadacitinib?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine is live attenuated, and upadacitinib-related immunosuppression may permit vaccine virus replication and illness. The vaccine response may also be reduced.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use an inactivated injectable influenza vaccine instead during upadacitinib therapy.
What other medicines interact with Upadacitinib?
MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.
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