Interações medicamentosas
Dengue vaccine + Upadacitinib
Gravidade: Contraindicada
Dengue vaccine and Upadacitinib: contraindicated interaction.
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Resumo
The dengue vaccine is live attenuated, and immunosuppression from upadacitinib may allow uncontrolled vaccine virus replication. The immune response may also be inadequate.
O que esta interação significa em palavras simples
Dengue vaccine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Immunosuppression impairs control of live attenuated virus and reduces vaccine response.
O que fazer
Avoid the live dengue vaccine during upadacitinib treatment. Vaccinate before starting therapy where indicated.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Upadacitinib
- Abrocitinib + Upadacitinib Contraindicada
- Adenovirus types 4 and 7 live + Upadacitinib Contraindicada
- Baricitinib + Upadacitinib Contraindicada
- Bcg vaccine live + Upadacitinib Contraindicada
- Cyclosporine + Upadacitinib Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Upadacitinib Contraindicada
Perguntas frequentes
Can I take Dengue vaccine with Upadacitinib?
MediHelp rates the interaction as contraindicated. Dengue vaccine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The dengue vaccine is live attenuated, and immunosuppression from upadacitinib may allow uncontrolled vaccine virus replication. The immune response may also be inadequate.
How serious is the interaction between Dengue vaccine and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live dengue vaccine during upadacitinib treatment. Vaccinate before starting therapy where indicated.
What other medicines interact with Upadacitinib?
MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.
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