Interações medicamentosas
Bcg vaccine live + Upadacitinib
Gravidade: Contraindicada
Bcg vaccine live and Upadacitinib: contraindicated interaction.
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Resumo
Upadacitinib-induced immunosuppression raises the risk of disseminated BCG infection after a live BCG vaccine. The vaccine response may also be reduced.
O que esta interação significa em palavras simples
Bcg vaccine live and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Immunosuppression impairs control of live attenuated mycobacteria.
O que fazer
Avoid live BCG vaccination during upadacitinib treatment. Complete needed vaccination before starting therapy, allowing at least 4 weeks.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Upadacitinib
- Abrocitinib + Upadacitinib Contraindicada
- Adenovirus types 4 and 7 live + Upadacitinib Contraindicada
- Baricitinib + Upadacitinib Contraindicada
- Cyclosporine + Upadacitinib Contraindicada
- Dengue vaccine + Upadacitinib Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Upadacitinib Contraindicada
Perguntas frequentes
Can I take Bcg vaccine live with Upadacitinib?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Upadacitinib-induced immunosuppression raises the risk of disseminated BCG infection after a live BCG vaccine. The vaccine response may also be reduced.
How serious is the interaction between Bcg vaccine live and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG vaccination during upadacitinib treatment. Complete needed vaccination before starting therapy, allowing at least 4 weeks.
What other medicines interact with Upadacitinib?
MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.
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