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Interações medicamentosas

Bevacizumab + Dengue vaccine

Gravidade: Moderada

Bevacizumab and Dengue vaccine: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

The dengue vaccine is live attenuated, and patients receiving cancer therapy may mount a weaker response. Bevacizumab itself is not strongly immunosuppressive, so the interaction is mainly relevant when it is combined with chemotherapy.

O que esta interação significa em palavras simples

Bevacizumab and Dengue vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Low

Por que acontece

Concurrent antineoplastic therapy may impair immune response and increase risk with a live vaccine; bevacizumab's own contribution is unclear.

O que fazer

Avoid live vaccines in patients on active chemotherapy-containing regimens; schedule vaccination before treatment or after immune recovery.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Bevacizumab with Dengue vaccine?

MediHelp rates the interaction as moderate. Bevacizumab and Dengue vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The dengue vaccine is live attenuated, and patients receiving cancer therapy may mount a weaker response. Bevacizumab itself is not strongly immunosuppressive, so the interaction is mainly relevant when it is combined with chemotherapy.

How serious is the interaction between Bevacizumab and Dengue vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines in patients on active chemotherapy-containing regimens; schedule vaccination before treatment or after immune recovery.

What other medicines interact with Bevacizumab?

MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Doxorubicin. The full list is on the Bevacizumab page.

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