Interações medicamentosas
Bevacizumab + Daunorubicin
Gravidade: Moderada
Bevacizumab and Daunorubicin: moderate interaction.
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Resumo
Daunorubicin is cardiotoxic, and bevacizumab can cause hypertension and, less commonly, heart failure. Combined use may increase cardiac risk, particularly in patients with prior anthracycline exposure.
O que esta interação significa em palavras simples
Bevacizumab and Daunorubicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bevacizumab belongs to Oncology; Daunorubicin belongs to Oncology.
Por que acontece
Additive cardiotoxicity from anthracycline myocardial injury and VEGF inhibition-related hypertension and cardiac stress.
O que fazer
Assess left ventricular function before and during treatment and monitor blood pressure. Treat hypertension promptly and stop therapy if heart failure develops.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Daunorubicin
- Adenovirus types 4 and 7 live + Daunorubicin Contraindicada
- Belatacept + Daunorubicin Grave
- Cyclosporine + Daunorubicin Grave
- Cyclosporin + Daunorubicin Grave
- Daunorubicin + Dengue vaccine Grave
- Daunorubicin + Etrasimod Grave
Outras interações de Bevacizumab
- Bevacizumab + Sunitinib Grave
- Bevacizumab + Dengue vaccine Moderada
- Bevacizumab + Doxorubicin Moderada
- Bevacizumab + Doxorubicin liposomal Moderada
- Bevacizumab + Efgartigimod / hyaluronidase sc Moderada
- Bevacizumab + Efgartigimod alfa Moderada
Perguntas frequentes
Can I take Bevacizumab with Daunorubicin?
MediHelp rates the interaction as moderate. Bevacizumab and Daunorubicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Daunorubicin is cardiotoxic, and bevacizumab can cause hypertension and, less commonly, heart failure. Combined use may increase cardiac risk, particularly in patients with prior anthracycline exposure.
How serious is the interaction between Bevacizumab and Daunorubicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess left ventricular function before and during treatment and monitor blood pressure. Treat hypertension promptly and stop therapy if heart failure develops.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclosporine. The full list is on the Daunorubicin page.
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