Interações medicamentosas
Bevacizumab + Doxorubicin liposomal
Gravidade: Moderada
Bevacizumab and Doxorubicin liposomal: moderate interaction.
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Resumo
Both agents have been associated with cardiac dysfunction, and bevacizumab can cause hypertension and heart failure. Together the risk of cardiomyopathy may be increased.
O que esta interação significa em palavras simples
Bevacizumab and Doxorubicin liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive cardiotoxicity from anthracycline myocardial injury and bevacizumab-related hypertension and cardiac dysfunction.
O que fazer
Assess left ventricular ejection fraction before and during treatment and monitor blood pressure; stop or modify therapy if heart failure develops.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Bevacizumab
- Bevacizumab + Sunitinib Grave
- Bevacizumab + Daunorubicin Moderada
- Bevacizumab + Dengue vaccine Moderada
- Bevacizumab + Doxorubicin Moderada
- Bevacizumab + Efgartigimod / hyaluronidase sc Moderada
- Bevacizumab + Efgartigimod alfa Moderada
Perguntas frequentes
Can I take Bevacizumab with Doxorubicin liposomal?
MediHelp rates the interaction as moderate. Bevacizumab and Doxorubicin liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents have been associated with cardiac dysfunction, and bevacizumab can cause hypertension and heart failure. Together the risk of cardiomyopathy may be increased.
How serious is the interaction between Bevacizumab and Doxorubicin liposomal?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess left ventricular ejection fraction before and during treatment and monitor blood pressure; stop or modify therapy if heart failure develops.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Dengue vaccine. The full list is on the Bevacizumab page.
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