Interações medicamentosas
Calcium carbonate + Vadadustat
Gravidade: Moderada
Calcium carbonate and Vadadustat: moderate interaction.
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Resumo
Calcium-based phosphate binders can bind vadadustat in the gut and lower its absorption. Reduced exposure may blunt its effect on hemoglobin.
O que esta interação significa em palavras simples
Calcium carbonate and Vadadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Vadadustat belongs to Endocrine.
Por que acontece
Binding of vadadustat by calcium-based phosphate binders in the gastrointestinal tract reduces absorption.
O que fazer
Take vadadustat at least 1 hour before or 2 hours after calcium carbonate used as a phosphate binder. Monitor hemoglobin.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Calcium carbonate
Outras interações de Vadadustat
- Atorvastatin + Vadadustat Moderada
- Balsalazide + Vadadustat Moderada
- Baricitinib + Vadadustat Moderada
- Benzathine penicillin g + Vadadustat Moderada
- Calcium + Vadadustat Moderada
- Cladribine + Vadadustat Moderada
Perguntas frequentes
Can I take Calcium carbonate with Vadadustat?
MediHelp rates the interaction as moderate. Calcium carbonate and Vadadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium-based phosphate binders can bind vadadustat in the gut and lower its absorption. Reduced exposure may blunt its effect on hemoglobin.
How serious is the interaction between Calcium carbonate and Vadadustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take vadadustat at least 1 hour before or 2 hours after calcium carbonate used as a phosphate binder. Monitor hemoglobin.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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