Interações medicamentosas
Cefotaxime + Microbiota
Gravidade: Moderada
Cefotaxime and Microbiota: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
O que esta interação significa em palavras simples
Cefotaxime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Antibacterial activity against the live bacterial components of the product reduces colonization (pharmacodynamic antagonism).
O que fazer
Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefotaxime
- Cefotaxime + Typhoid vaccine live Grave
- Amikacin + Cefotaxime Moderada
- Cefotaxime + Cholera vaccine Moderada
- Cefotaxime + Dexamethasone-tobramycin Moderada
- Cefotaxime + Gentamicin Moderada
- Cefotaxime + Kanamycin Moderada
Perguntas frequentes
Can I take Cefotaxime with Microbiota?
MediHelp rates the interaction as moderate. Cefotaxime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
How serious is the interaction between Cefotaxime and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
What other medicines interact with Cefotaxime?
MediHelp also lists interactions of Cefotaxime with, for example, Typhoid vaccine live, Amikacin, Cholera vaccine. The full list is on the Cefotaxime page.
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