Interações medicamentosas
Charcoal + Citalopram
Gravidade: Moderada
Charcoal and Citalopram: moderate interaction.
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Resumo
Activated charcoal binds citalopram in the gut and reduces its absorption. With therapeutic dosing this could lower efficacy, whereas in overdose this effect is intentionally used to limit toxicity.
O que esta interação significa em palavras simples
Charcoal and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Charcoal belongs to Gastrointestinal Tract; Citalopram belongs to Central Nervous System.
Por que acontece
Charcoal adsorbs citalopram in the gastrointestinal tract, reducing its absorption.
O que fazer
Separate therapeutic citalopram doses from charcoal by at least 2 hours, ideally giving citalopram well before charcoal. In overdose, give charcoal as indicated and monitor ECG and for serotonin toxicity.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Charcoal
- Charcoal + Digoxin Moderada
- Charcoal + Leflunomide Moderada
- Charcoal + Methotrexate Moderada
- Charcoal + Theophylline Moderada
- Charcoal + Tiratricol Moderada
- Acarbose + Charcoal Leve
Outras interações de Citalopram
- Cisapride + Citalopram Contraindicada
- Citalopram + Dronedarone Contraindicada
- Citalopram + Escitalopram Contraindicada
- Citalopram + Isocarboxazid Contraindicada
- Citalopram + Methylene blue Contraindicada
- Citalopram + Phenelzine Contraindicada
Perguntas frequentes
Can I take Charcoal with Citalopram?
MediHelp rates the interaction as moderate. Charcoal and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Activated charcoal binds citalopram in the gut and reduces its absorption. With therapeutic dosing this could lower efficacy, whereas in overdose this effect is intentionally used to limit toxicity.
How serious is the interaction between Charcoal and Citalopram?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate therapeutic citalopram doses from charcoal by at least 2 hours, ideally giving citalopram well before charcoal. In overdose, give charcoal as indicated and monitor ECG and for serotonin toxicity.
What other medicines interact with Charcoal?
MediHelp also lists interactions of Charcoal with, for example, Digoxin, Leflunomide, Methotrexate. The full list is on the Charcoal page.
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