Interações medicamentosas
Charcoal + Theophylline
Gravidade: Moderada
Charcoal and Theophylline: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Activated charcoal binds theophylline in the gut and increases its elimination, including from the circulation with repeated doses. This reduces bronchodilator effect at therapeutic doses but is valuable in theophylline overdose.
O que esta interação significa em palavras simples
Charcoal and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Charcoal belongs to Gastrointestinal Tract; Theophylline belongs to Respiratory.
Por que acontece
Charcoal adsorbs theophylline in the gut and enhances its elimination by gastrointestinal dialysis.
O que fazer
Avoid concurrent charcoal during therapeutic theophylline use or separate doses by several hours. In overdose, give repeated-dose charcoal and monitor serum theophylline levels.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Charcoal
- Charcoal + Citalopram Moderada
- Charcoal + Digoxin Moderada
- Charcoal + Leflunomide Moderada
- Charcoal + Methotrexate Moderada
- Charcoal + Tiratricol Moderada
- Acarbose + Charcoal Leve
Outras interações de Theophylline
- Riociguat + Theophylline Contraindicada
- Adenosine + Theophylline Grave
- Apalutamide + Theophylline Grave
- Bupropion + Theophylline Grave
- Carvedilol + Theophylline Grave
- Cimetidine + Theophylline Grave
Perguntas frequentes
Can I take Charcoal with Theophylline?
MediHelp rates the interaction as moderate. Charcoal and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Activated charcoal binds theophylline in the gut and increases its elimination, including from the circulation with repeated doses. This reduces bronchodilator effect at therapeutic doses but is valuable in theophylline overdose.
How serious is the interaction between Charcoal and Theophylline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent charcoal during therapeutic theophylline use or separate doses by several hours. In overdose, give repeated-dose charcoal and monitor serum theophylline levels.
What other medicines interact with Charcoal?
MediHelp also lists interactions of Charcoal with, for example, Citalopram, Digoxin, Leflunomide. The full list is on the Charcoal page.
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