Interações medicamentosas
Bupropion + Theophylline
Gravidade: Grave
Bupropion and Theophylline: major interaction.
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Both theophylline and bupropion lower the seizure threshold, so combined use increases the risk of seizures. This is particularly relevant when theophylline levels are elevated or bupropion doses are high.
O que esta interação significa em palavras simples
Bupropion and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bupropion belongs to Central Nervous System; Theophylline belongs to Respiratory.
Por que acontece
Additive pharmacodynamic lowering of the seizure threshold.
O que fazer
Avoid the combination when possible, or use the lowest effective bupropion dose with gradual titration. Keep theophylline levels within the therapeutic range and avoid in patients with other seizure risk factors.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Bupropion e Theophylline, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Referências
- buPropion Hydrochloride XL - FDA drug label (DailyMed) — openFDA / DailyMed
Outras interações de Theophylline
- Riociguat + Theophylline Contraindicada
- Adenosine + Theophylline Grave
- Apalutamide + Theophylline Grave
- Carvedilol + Theophylline Grave
- Cimetidine + Theophylline Grave
- Ciprofloxacin + Theophylline Grave
Outras interações de Bupropion
- Bupropion + Isocarboxazid Contraindicada
- Bupropion + Linezolid Contraindicada
- Bupropion + Phenelzine Contraindicada
- Bupropion + Rasagiline Contraindicada
- Bupropion + Selegiline Contraindicada
- Bupropion + Selegiline transdermal Contraindicada
Perguntas frequentes
Can I take Bupropion with Theophylline?
MediHelp rates the interaction as major. Bupropion and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both theophylline and bupropion lower the seizure threshold, so combined use increases the risk of seizures. This is particularly relevant when theophylline levels are elevated or bupropion doses are high.
How serious is the interaction between Bupropion and Theophylline?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination when possible, or use the lowest effective bupropion dose with gradual titration. Keep theophylline levels within the therapeutic range and avoid in patients with other seizure risk factors.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
