Interações medicamentosas
Cidofovir + Vancomycin
Gravidade: Grave
Cidofovir and Vancomycin: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Both drugs can injure the kidney, and combined use may raise the risk of acute kidney injury. Cidofovir carries a boxed warning for renal toxicity and its label advises against use with other nephrotoxic agents.
O que esta interação significa em palavras simples
Cidofovir and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cidofovir belongs to Anti Virals; Vancomycin belongs to Anti Bacterial.
Por que acontece
Additive nephrotoxicity, with cidofovir causing proximal tubular injury and vancomycin contributing tubular toxicity.
O que fazer
Avoid concurrent use where possible; if unavoidable, ensure hydration with probenecid per cidofovir protocol and monitor serum creatinine and urinalysis before each cidofovir dose. Consider alternatives to vancomycin.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Vancomycin
- Amikacin + Vancomycin Grave
- Bacitracin + Vancomycin Grave
- Capreomycin + Vancomycin Grave
- Cephaloridine + Vancomycin Grave
- Cisplatin + Vancomycin Grave
- Colistin + Vancomycin Grave
Outras interações de Cidofovir
- Amikacin + Cidofovir Contraindicada
- Amphotericin b deoxycholate + Cidofovir Contraindicada
- Amphotericin b + Cidofovir Contraindicada
- Bacitracin + Cidofovir Contraindicada
- Capreomycin + Cidofovir Contraindicada
- Cephaloridine + Cidofovir Contraindicada
Perguntas frequentes
Can I take Cidofovir with Vancomycin?
MediHelp rates the interaction as major. Cidofovir and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can injure the kidney, and combined use may raise the risk of acute kidney injury. Cidofovir carries a boxed warning for renal toxicity and its label advises against use with other nephrotoxic agents.
How serious is the interaction between Cidofovir and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible; if unavoidable, ensure hydration with probenecid per cidofovir protocol and monitor serum creatinine and urinalysis before each cidofovir dose. Consider alternatives to vancomycin.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Bacitracin, Capreomycin. The full list is on the Vancomycin page.
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