Interações medicamentosas
Bacitracin + Vancomycin
Gravidade: Grave
Bacitracin and Vancomycin: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Both drugs can injure the kidney, and systemic bacitracin in particular causes dose-related renal tubular damage. Giving them together, especially when vancomycin is parenteral, raises the risk of acute kidney injury, and ototoxicity from vancomycin may add to the concern.
O que esta interação significa em palavras simples
Bacitracin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Vancomycin belongs to Anti Bacterial.
Por que acontece
Additive nephrotoxicity from two agents that each damage renal tubular cells.
O que fazer
Avoid systemic bacitracin with vancomycin; if unavoidable, monitor serum creatinine and urine output frequently and adjust doses to renal function and vancomycin levels.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Vancomycin
- Amikacin + Vancomycin Grave
- Capreomycin + Vancomycin Grave
- Cephaloridine + Vancomycin Grave
- Cidofovir + Vancomycin Grave
- Cisplatin + Vancomycin Grave
- Colistin + Vancomycin Grave
Outras interações de Bacitracin
- Bacitracin + Cidofovir Contraindicada
- Adefovir + Bacitracin Grave
- Aldesleukin + Bacitracin Grave
- Amikacin + Bacitracin Grave
- Bacitracin + Carboplatin Grave
- Bacitracin + Cisplatin Grave
Perguntas frequentes
Can I take Bacitracin with Vancomycin?
MediHelp rates the interaction as major. Bacitracin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can injure the kidney, and systemic bacitracin in particular causes dose-related renal tubular damage. Giving them together, especially when vancomycin is parenteral, raises the risk of acute kidney injury, and ototoxicity from vancomycin may add to the concern.
How serious is the interaction between Bacitracin and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic bacitracin with vancomycin; if unavoidable, monitor serum creatinine and urine output frequently and adjust doses to renal function and vancomycin levels.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Capreomycin, Cephaloridine. The full list is on the Vancomycin page.
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