Interações medicamentosas
Capreomycin + Vancomycin
Gravidade: Grave
Capreomycin and Vancomycin: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Both drugs can damage the kidneys and the inner ear, so combined use may increase the risk of nephrotoxicity and ototoxicity. Capreomycin is itself a significant nephrotoxin and ototoxin, so the combination deserves more than minor concern.
O que esta interação significa em palavras simples
Capreomycin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Additive nephrotoxic and ototoxic effects of both agents.
O que fazer
Avoid the combination where possible; if unavoidable, monitor serum creatinine, vancomycin trough levels and hearing regularly and adjust doses to renal function.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Vancomycin
- Amikacin + Vancomycin Grave
- Bacitracin + Vancomycin Grave
- Cephaloridine + Vancomycin Grave
- Cidofovir + Vancomycin Grave
- Cisplatin + Vancomycin Grave
- Colistin + Vancomycin Grave
Perguntas frequentes
Can I take Capreomycin with Vancomycin?
MediHelp rates the interaction as major. Capreomycin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can damage the kidneys and the inner ear, so combined use may increase the risk of nephrotoxicity and ototoxicity. Capreomycin is itself a significant nephrotoxin and ototoxin, so the combination deserves more than minor concern.
How serious is the interaction between Capreomycin and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if unavoidable, monitor serum creatinine, vancomycin trough levels and hearing regularly and adjust doses to renal function.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Bacitracin, Cephaloridine. The full list is on the Vancomycin page.
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