Interações medicamentosas
Dexlansoprazole + Itraconazole
Gravidade: Grave
Dexlansoprazole and Itraconazole: major interaction.
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Resumo
Acid suppression lowers absorption of itraconazole capsules, risking subtherapeutic antifungal levels and treatment failure.
O que esta interação significa em palavras simples
Dexlansoprazole and Itraconazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexlansoprazole belongs to Gastrointestinal Tract; Itraconazole belongs to Anti Fungals.
Por que acontece
Raised gastric pH decreases dissolution and absorption of itraconazole capsules.
O que fazer
Avoid with itraconazole capsules or use the oral solution. Monitor itraconazole levels and clinical response.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Dexlansoprazole
- Dexlansoprazole + Mavacamten Contraindicada
- Dexlansoprazole + Rilpivirine Contraindicada
- Acalabrutinib + Dexlansoprazole Grave
- Atazanavir + Dexlansoprazole Grave
- Dacomitinib + Dexlansoprazole Grave
- Dasatinib + Dexlansoprazole Grave
Outras interações de Itraconazole
- Alfuzosin + Itraconazole Contraindicada
- Alprazolam + Itraconazole Contraindicada
- Avanafil + Itraconazole Contraindicada
- Conivaptan + Itraconazole Contraindicada
- Dihydroergotamine intranasal + Itraconazole Contraindicada
- Dihydroergotamine + Itraconazole Contraindicada
Perguntas frequentes
Can I take Dexlansoprazole with Itraconazole?
MediHelp rates the interaction as major. Dexlansoprazole and Itraconazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Acid suppression lowers absorption of itraconazole capsules, risking subtherapeutic antifungal levels and treatment failure.
How serious is the interaction between Dexlansoprazole and Itraconazole?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid with itraconazole capsules or use the oral solution. Monitor itraconazole levels and clinical response.
What other medicines interact with Dexlansoprazole?
MediHelp also lists interactions of Dexlansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Dexlansoprazole page.
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