Referência de medicamentos
Dexlansoprazole
Dexlansoprazole is a medicine in the class gastrointestinal tract. It is used for gerd.
- Classe do medicamento: Gastrointestinal Tract
- Indicado para: gerd
Última atualização
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O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Gastrointestinal Tract
- Formas farmacêuticas comuns
- cápsula
- Concentrações comuns
- 60 mg, 30 mg
- Interações conhecidas
- 116 (Contraindicada: 2 · Grave: 18 · Moderada: 46 · Leve: 50)
- Nomes comerciais
- 22
- Países e mercados
- 4
Para que é usado
Como funciona
R-enantiomer of lansoprazole; PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion, Dual release formulation, Relative Potency: not available.
Dose habitual em adultos (resumo da bula)
General dosing: 30-60 mg orally every day for up to 8 weeks.
Como costuma ser tomado
Proton pump inhibitors are usually taken by mouth once a day, often before a meal, for a course whose length depends on the reason for treatment.
Gravidez e amamentação
- Gravidez
- Safe No human studies, but data for lansoprazole, of which it is an enantiomer, show no harm in pregnancy. Acceptable when a PPI is needed; omeprazole has the most pregnancy data.
- Amamentação
- Safe No milk data. LactMed: as lansoprazole has been used safely in newborns, the amount in milk is unlikely to harm the infant. Acceptable.
Efeitos adversos relatados
- Vomiting
- Diarrhea
- Nausea
- Abdominal pain
- URI
Contraindicações
- Hypersensitivity reactions, including anaphylaxis and acute interstitial nephritis reported
- PPIs are contraindicated with rilpivirine-containing products
Quem deve ter cuidado
- Proton pump inhibitors (PPIs) are possibly associated with increased incidence of Clostridium difficile-associated diarrhea (CDAD).
- PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, particularly with prolonged (>1 yr), high-dose therapy.
- Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.
People taking proton pump inhibitors for a long time should have the need for treatment reviewed, because long-term use is linked to low magnesium, vitamin B12 deficiency, bone fractures and gut infections. Tell your pharmacist about all other medicines, since some interact.
Informe ao farmacêutico ou ao médico sobre gravidez ou amamentação, doença renal ou hepática, alergias e todos os outros medicamentos ou suplementos que você usa.
Principais interações (116)
- Dexlansoprazole + Mavacamten Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Dexlansoprazole Major
- Atazanavir + Dexlansoprazole Major
- Dacomitinib + Dexlansoprazole Major
- Dasatinib + Dexlansoprazole Major
- Dexlansoprazole + Erlotinib Major
- Dexlansoprazole + Gefitinib Major
- Dexlansoprazole + Infigratinib Major
- Dexlansoprazole + Itraconazole Major
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- Renal and hepatic dose adjustments
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Outros medicamentos desta classe
Perguntas frequentes
What is Dexlansoprazole used for?
Dexlansoprazole is a medicine in the class gastrointestinal tract. It is used for GERD, Peptic ulcer.
What side effects have been reported with Dexlansoprazole?
Vomiting, Diarrhea, Nausea, Abdominal pain, URI.
Can Dexlansoprazole be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. No human studies, but data for lansoprazole, of which it is an enantiomer, show no harm in pregnancy. Acceptable when a PPI is needed; omeprazole has the most pregnancy data. Breastfeeding: Safe. No milk data. LactMed: as lansoprazole has been used safely in newborns, the amount in milk is unlikely to harm the infant. Acceptable.
What does Dexlansoprazole interact with?
MediHelp lists 116 known interactions for Dexlansoprazole. Contraindicated: 2 · Major: 18 · Moderate: 46 · Minor: 50. The most serious include Mavacamten, Rilpivirine, Acalabrutinib.
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