Interações medicamentosas
Dexmethylphenidate + Selegiline
Gravidade: Contraindicada
Dexmethylphenidate and Selegiline: contraindicated interaction.
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Resumo
MAO inhibitors combined with methylphenidate-type stimulants can provoke severe hypertensive crisis. Labeling contraindicates dexmethylphenidate during MAOI therapy and for 14 days afterward.
O que esta interação significa em palavras simples
Dexmethylphenidate and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Selegiline belongs to Central Nervous System.
Por que acontece
The stimulant releases catecholamines, and MAO inhibition prevents their degradation, so they accumulate.
O que fazer
Do not combine. Allow at least 14 days after stopping the MAOI before starting dexmethylphenidate.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Selegiline
- Amitriptyline + Selegiline Contraindicada
- Amoxapine + Selegiline Contraindicada
- Atomoxetine + Selegiline Contraindicada
- Benzphetamine + Selegiline Contraindicada
- Brimonidine + Selegiline Contraindicada
- Buprenorphine long-acting + Selegiline Contraindicada
Outras interações de Dexmethylphenidate
- Dexmethylphenidate + Isocarboxazid Contraindicada
- Dexmethylphenidate + Linezolid Contraindicada
- Dexmethylphenidate + Phenelzine Contraindicada
- Dexmethylphenidate + Procarbazine Contraindicada
- Dexmethylphenidate + Rasagiline Contraindicada
- Dexmethylphenidate + Safinamide Contraindicada
Perguntas frequentes
Can I take Dexmethylphenidate with Selegiline?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAO inhibitors combined with methylphenidate-type stimulants can provoke severe hypertensive crisis. Labeling contraindicates dexmethylphenidate during MAOI therapy and for 14 days afterward.
How serious is the interaction between Dexmethylphenidate and Selegiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Allow at least 14 days after stopping the MAOI before starting dexmethylphenidate.
What other medicines interact with Selegiline?
MediHelp also lists interactions of Selegiline with, for example, Amitriptyline, Amoxapine, Atomoxetine. The full list is on the Selegiline page.
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