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Interações medicamentosas

Dexmethylphenidate + Phenelzine

Gravidade: Contraindicada

Dexmethylphenidate and Phenelzine: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Dexmethylphenidate with MAO inhibitors may cause hypertensive crisis. Severe headache, very high blood pressure and cerebrovascular events are possible.

O que esta interação significa em palavras simples

Dexmethylphenidate and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Dexmethylphenidate belongs to Central Nervous System; Phenelzine belongs to Central Nervous System.

Nível de evidência: High

Por que acontece

MAO inhibition increases catecholamine stores, and dexmethylphenidate increases synaptic catecholamines, producing an exaggerated pressor response.

O que fazer

Do not use during phenelzine therapy or within 14 days of stopping it. Select a non-stimulant alternative.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Dexmethylphenidate with Phenelzine?

MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dexmethylphenidate with MAO inhibitors may cause hypertensive crisis. Severe headache, very high blood pressure and cerebrovascular events are possible.

How serious is the interaction between Dexmethylphenidate and Phenelzine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use during phenelzine therapy or within 14 days of stopping it. Select a non-stimulant alternative.

What other medicines interact with Phenelzine?

MediHelp also lists interactions of Phenelzine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Phenelzine page.

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