Interações medicamentosas
Dexmethylphenidate + Linezolid
Gravidade: Contraindicada
Dexmethylphenidate and Linezolid: contraindicated interaction.
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Resumo
Dexmethylphenidate increases synaptic norepinephrine and dopamine, and linezolid blocks their breakdown. This can provoke hypertensive crisis.
O que esta interação significa em palavras simples
Dexmethylphenidate and Linezolid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Linezolid belongs to Anti Bacterial.
Por que acontece
MAO inhibition by linezolid potentiates catecholamines released or retained by dexmethylphenidate.
O que fazer
Avoid combination and do not give dexmethylphenidate during or within 14 days of an MAOI. If linezolid is essential, hold the stimulant and monitor blood pressure.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Linezolid
- Amoxapine + Linezolid Contraindicada
- Atomoxetine + Linezolid Contraindicada
- Benzphetamine + Linezolid Contraindicada
- Brimonidine + Linezolid Contraindicada
- Bupropion-naltrexone + Linezolid Contraindicada
- Bupropion + Linezolid Contraindicada
Outras interações de Dexmethylphenidate
- Dexmethylphenidate + Isocarboxazid Contraindicada
- Dexmethylphenidate + Phenelzine Contraindicada
- Dexmethylphenidate + Procarbazine Contraindicada
- Dexmethylphenidate + Rasagiline Contraindicada
- Dexmethylphenidate + Safinamide Contraindicada
- Dexmethylphenidate + Selegiline Contraindicada
Perguntas frequentes
Can I take Dexmethylphenidate with Linezolid?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Linezolid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dexmethylphenidate increases synaptic norepinephrine and dopamine, and linezolid blocks their breakdown. This can provoke hypertensive crisis.
How serious is the interaction between Dexmethylphenidate and Linezolid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination and do not give dexmethylphenidate during or within 14 days of an MAOI. If linezolid is essential, hold the stimulant and monitor blood pressure.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
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