Interações medicamentosas
Digoxin + Teriparatide
Gravidade: Moderada
Digoxin and Teriparatide: moderate interaction.
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Resumo
Teriparatide can cause transient rises in serum calcium after dosing. Hypercalcemia increases myocardial sensitivity to digoxin, so toxicity could theoretically occur, although reports are rare.
O que esta interação significa em palavras simples
Digoxin and Teriparatide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Teriparatide belongs to Musculoskeletal.
Por que acontece
Transient teriparatide-induced hypercalcemia sensitizes the myocardium to digitalis glycosides, increasing arrhythmia risk.
O que fazer
Monitor serum calcium and digoxin levels, and watch for signs of digoxin toxicity such as nausea, visual changes and arrhythmias. Adjust the digoxin dose if toxicity is suspected.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Teriparatide
Outras interações de Digoxin
- Digoxin + Lily of the valley Contraindicada
- Digoxin + Squill Contraindicada
- Adagrasib + Digoxin Grave
- Amiodarone + Digoxin Grave
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Grave
- Amphotericin b deoxycholate + Digoxin Grave
Perguntas frequentes
Can I take Digoxin with Teriparatide?
MediHelp rates the interaction as moderate. Digoxin and Teriparatide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teriparatide can cause transient rises in serum calcium after dosing. Hypercalcemia increases myocardial sensitivity to digoxin, so toxicity could theoretically occur, although reports are rare.
How serious is the interaction between Digoxin and Teriparatide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and digoxin levels, and watch for signs of digoxin toxicity such as nausea, visual changes and arrhythmias. Adjust the digoxin dose if toxicity is suspected.
What other medicines interact with Teriparatide?
MediHelp also lists interactions of Teriparatide with, for example, Alendronate, Calcium acetate, Calcium carbonate. The full list is on the Teriparatide page.
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