Interações medicamentosas
Dihydroergotamine + Voriconazole
Gravidade: Contraindicada
Dihydroergotamine and Voriconazole: contraindicated interaction.
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Resumo
Voriconazole raises dihydroergotamine levels and risks ergotism, with severe peripheral and cerebral vasospasm and ischemia. The outcome can be limb or organ threatening.
O que esta interação significa em palavras simples
Dihydroergotamine and Voriconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Voriconazole belongs to Anti Fungals.
Por que acontece
Strong CYP3A4 inhibition by voriconazole reduces dihydroergotamine metabolism.
O que fazer
Do not use together; choose a non-ergot migraine therapy during voriconazole treatment.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Voriconazole
- Avanafil + Voriconazole Contraindicada
- Butabarbital + Voriconazole Contraindicada
- Carbamazepine + Voriconazole Contraindicada
- Conivaptan + Voriconazole Contraindicada
- Dihydroergotamine intranasal + Voriconazole Contraindicada
- Dofetilide + Voriconazole Contraindicada
Outras interações de Dihydroergotamine
- Almotriptan + Dihydroergotamine Contraindicada
- Clarithromycin + Dihydroergotamine Contraindicada
- Dihydroergotamine + Dopamine Contraindicada
- Dihydroergotamine + Dronedarone Contraindicada
- Dihydroergotamine + Efavirenz Contraindicada
- Dihydroergotamine + Eletriptan Contraindicada
Perguntas frequentes
Can I take Dihydroergotamine with Voriconazole?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Voriconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Voriconazole raises dihydroergotamine levels and risks ergotism, with severe peripheral and cerebral vasospasm and ischemia. The outcome can be limb or organ threatening.
How serious is the interaction between Dihydroergotamine and Voriconazole?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose a non-ergot migraine therapy during voriconazole treatment.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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