Interações medicamentosas
Foscarnet + Zoledronic acid
Gravidade: Moderada
Foscarnet and Zoledronic acid: moderate interaction.
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Resumo
Both drugs lower serum calcium: zoledronic acid by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia, including tetany, paresthesias and seizures or arrhythmias.
O que esta interação significa em palavras simples
Foscarnet and Zoledronic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Zoledronic acid belongs to Musculoskeletal.
Por que acontece
Additive lowering of serum calcium through bone resorption inhibition and chelation of ionized calcium.
O que fazer
Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits. Replace calcium and vitamin D as needed.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Zoledronic acid
- Amikacin + Zoledronic acid Moderada
- Bumetanide + Zoledronic acid Moderada
- Dichlorphenamide + Zoledronic acid Moderada
- Ethacrynic acid + Zoledronic acid Moderada
- Gentamicin + Zoledronic acid Moderada
- Human parathyroid hormone recombinant + Zoledronic acid Moderada
Outras interações de Foscarnet
- Cidofovir + Foscarnet Contraindicada
- Foscarnet + Pimozide Contraindicada
- Foscarnet + Thioridazine Contraindicada
- Foscarnet + Vandetanib Contraindicada
- Adagrasib + Foscarnet Grave
- Adefovir + Foscarnet Grave
Perguntas frequentes
Can I take Foscarnet with Zoledronic acid?
MediHelp rates the interaction as moderate. Foscarnet and Zoledronic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower serum calcium: zoledronic acid by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia, including tetany, paresthesias and seizures or arrhythmias.
How serious is the interaction between Foscarnet and Zoledronic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits. Replace calcium and vitamin D as needed.
What other medicines interact with Zoledronic acid?
MediHelp also lists interactions of Zoledronic acid with, for example, Amikacin, Bumetanide, Dichlorphenamide. The full list is on the Zoledronic acid page.
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