Interações medicamentosas
Isocarboxazid + Oliceridine
Gravidade: Contraindicada
Isocarboxazid and Oliceridine: contraindicated interaction.
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Resumo
Opioids combined with MAOIs carry risk of serotonin syndrome and potentiated opioid effects including respiratory depression. Oliceridine labeling advises against use within 14 days of MAOIs.
O que esta interação significa em palavras simples
Isocarboxazid and Oliceridine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Isocarboxazid belongs to Central Nervous System; Oliceridine belongs to Musculoskeletal.
Por que acontece
MAO inhibition may cause serotonergic excess and potentiate opioid CNS and respiratory depression.
O que fazer
Avoid oliceridine during and within 14 days after stopping isocarboxazid; use a non-opioid or alternative analgesic.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Isocarboxazid
- 5-HTP + Isocarboxazid Contraindicada
- Amitriptyline + Isocarboxazid Contraindicada
- Amobarbital + Isocarboxazid Contraindicada
- Amoxapine + Isocarboxazid Contraindicada
- Apraclonidine + Isocarboxazid Contraindicada
- Atomoxetine + Isocarboxazid Contraindicada
Outras interações de Oliceridine
Perguntas frequentes
Can I take Isocarboxazid with Oliceridine?
MediHelp rates the interaction as contraindicated. Isocarboxazid and Oliceridine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Opioids combined with MAOIs carry risk of serotonin syndrome and potentiated opioid effects including respiratory depression. Oliceridine labeling advises against use within 14 days of MAOIs.
How serious is the interaction between Isocarboxazid and Oliceridine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid oliceridine during and within 14 days after stopping isocarboxazid; use a non-opioid or alternative analgesic.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
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